WordReference Random House Unabridged Dictionary of American English © 2025
alpha block′er, [Pharm.]
  1. Drugsany of various substances that interfere with the action of the alpha receptors.
Also, alpha-block′er. Cf. beta blocker.  alpha-block′ing, adj. 

Collins Concise English Dictionary © HarperCollins Publishers::
alpha-blocker
  1. any of a class of drugs that prevent the stimulation of alpha adrenoceptors, a type of receptor in the sympathetic nervous system, by adrenaline and noradrenaline and that therefore cause widening of blood vessels: used in the treatment of high blood pressure and prostatic hyperplasia
'alpha blocker' also found in these entries (note: many are not synonyms or translations):

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